THERAPY

Systemic corticosteroids are given to pemphigus patients. Initial dose must be at least 120 mg/day prednisolone or equivalent dose of another steroid. Dose may be increased until healing of the erosions and ceasing of the blister crops. After the control of the disease dose should be slowly decreased to maintenance dose prevents the exacerbations. Classically patient must be use corticosteroid lifelong.

Azathioprine and cyclophosphamide can never be used instead of corticosteroid, but combined with steroids. Such combination proves smaller corticosteroid doses. In combined therapy both of the drugs are decreased together. At the last cytostatic is stopped and steroid in the maintenance dose is used lifelong.